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A commonly-used drug to treat erectile dysfunction could be effective in treating long-term diabetic peripheral neuropathy. Peripheral neuropathy is the most common complication of diabetes and causes painful, life-threatening nerve damage in people with type 1 and type 2 diabetes. Researchers at the Henry Ford Hospital, United States tested sildenafil, known widely as Viagra, on male mice with diabetes. 15 mice were treated orally with sildenafil for eight weeks, while another group of 15 mice were given a saline solution daily.



Nerve and function tests were conducted on both groups of mice, with researchers observing that compared to the saline-treated mice, sildenafil improved sensory function starting at six weeks. In humans, sildenafil works by widening blood vessels and improving blood flow to the penis following sexual arousal.
Wang and his team have stressed that their findings are experimental, but hope that the development of a sildenafil treatment could result in a treatment for long-term diabetic peripheral neuropathy. To prevent diabetic peripheral neuropathy from developing, maintaining good control over blood glucose levels is recommended through diet and regular exercise. Find support, ask questions and share your experiences with 209,001 members of the diabetes community.
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Researchers at the University of Tubingen in Germany discovered that men who rely on the medication are at a greater risk of melanoma, which is the deadliest form of skin cancer.


The researchers noted that Sildenafil, which is marketed as Viagra and has been on the market since the late 1990s, has a stimulating effect on the messenger molecule cyclic guanosine monophosphate or cGMP, which in turn promotes the growth of existing malignant melanomas.
Study author Robert Feil said that they discovered that the cells of malignant melanoma also use the cGMP signaling pathway for their growth. Cells normally contain an enzyme, called phosphodiesterase type 5 (or PDE5), that ensures the newly-formed cGMP is continuously broken down. The views expressed in the contents above are those of our users and do not necessarily reflect the views of MailOnline. Both of which will support, guide, and inspire you toward the best possible health outcomes for you and your family. Previous studies have shown that patients with diabetes who took Viagra displayed fewer symptoms of peripheral neuropathy.



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