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Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.Dextromethorphan is a cough suppressant.
It affects the signals in the brain that trigger cough reflex.Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cough or cold medicine before the MAO inhibitor has cleared from your body. Do not use any other over-the-counter cough, cold, allergy, or sleep medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of one or more types of medicine. Read the label of any other medicine you are using to see if it contains an antihistamine, decongestant, or cough suppressant. Chlorpheniramine, dextromethorphan, and phenylephrine can cause side effects that may impair your thinking or reactions. It can increase some of the side effects of this medication.What should I discuss with my healthcare provider before taking Ed A-Hist DM (chlorpheniramine, dextromethorphan, and phenylephrine)?Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days.



Chlorpheniramine, dextromethorphan, and phenylephrine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.Artificially-sweetened liquid forms of cough-and-cold medications may contain phenylalanine. Check the ingredients and warnings on the medication label if you are concerned about phenylalanine.How should I take Ed A-Hist DM (chlorpheniramine, dextromethorphan, and phenylephrine)?Use this medication exactly as directed on the label or as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor.Always ask a doctor before giving a cough or cold medicine to a child.
If you use the effervescent tablet, drop the tablet in 8 ounces of water and allow it to dissolve completely. To make sure you get the entire dose, add a little more water to the same glass, swirl gently and drink right away.Measure the liquid form of this medicine with a special dose-measuring spoon or cup, not a regular table spoon. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Before taking this medication, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by this medication.Avoid taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor's advice.


Taking a stimulant together with a decongestant can increase your risk of unpleasant side effects.Do not use any other over-the-counter cough, cold, allergy, or sleep medication without first asking your doctor or pharmacist. Antihistamines, decongestants, and cough suppressants are contained in many medicines available over the counter. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides.
The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.Copyright 1996-2006 Cerner Multum, Inc.



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