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Description: This podcast covers several new topics, including celebrities who are convinced the earth is flat, the growing threat that is Zika virus, and how HIV is eluding CRISPR treatments. Keywords: glycans, glycobiology, podcast, Pascal Gagneux, sperm, evolution, biolegend, science, chimpanzees, non-human primates, Neanderthal, pathogen, Ajit Varki Having difficulty playing this episode? Description: In this episode, we discuss some a variety of current scientific news, including the discovery of woman who can smell Parkinson's disease, a correlation between bovine leukemia virus and breast cancer, using an individual's microbial cloud to identify them, and how we're using specialized antibodies to combat both HIV and cancer. Keywords: immunology, comics, cancer, chimeric antigen receptor, T cells, gene therapy, hypoxia, immune checkpoints, goinvivo, tumors, podcast, pedromics, pedro velica Having difficulty playing this episode?
Keywords: neuroscience, neurodegeneration, Parkinson's disease, microbes, microbial, gut microbiome, bacteria, asthma, allergy, leukemia, cancer, AML, antibody, virus, cow, bovine, breast cancer, HIV, AIDS Having difficulty playing this episode? Description: Special guest and global health scientist Jessica Taaffe joins us to discuss educating the public, funding research, and the passion needed in scientific role models. Keywords: global health, Jessica Taaffe, HIV, ebola, education, Bill Nye, Neil degrasse Tyson, vaccines, anti-vaxxers, world bank, funding, research, NIH, primates, biolegend, podcast Having difficulty playing this episode? Description: The podcast team discusses the potential anti-venom shortage, a wasp-venom derived protein for cancer therapy, 30,000 year-old viruses, and a new hominid species discovered in South Africa. Keywords: venom, anti-venom, snakebites, wasp venom, Fav-Afrique, MP1, Polybia-MP1, Polybia paulista, phosphatidylserine, annexin V, cancer cells, homo naledi, fossils, Mollivirus sibericum, viruses, Siberia, giant viruses Having difficulty playing this episode? Description: On this podcast, we discuss current events in science, including recent outbreaks of polio in the Ukraine and Legionnaire's disease in California and Illinois.
Keywords: polio, Legionnaire's disease, outbreaks, virus, bacteria, saturated fats, obesity, microbiome, mice, inflammation, leptin, neurons, brain, exercise, neutrophils, T cells, infection, lungs, influenza, open-access, journal, the wall of polio, science, podcast, virology, immunology Having difficulty playing this episode? Description: Glioblastomas and medulloblastomas are two common forms of brain cancer that afflicts thousands of people a year. Description: We cover the latest science current events, including the new Ebola vaccine, limb regeneration, being hangry, and Kim K's flub with the FDA. Keywords: Kim Kardashian, ebola, vaccines, anti-vaxxers, current events, limb regeneration, repair, hangry, science, podcast, food and drug administration, morning sickness, FDA Having difficulty playing this episode? Description: In our latest podcast, we talk about narcolepsy and the fight between local colleges for the rights to an Alzheimer's disease database. Keywords: UCSD, USC, University of Southern California, University of California San Diego, Alzheimer's disease, Pandemrix, narcolepsy, sleep, Paul Aisen, BioLegend, science, podcast Having difficulty playing this episode? Description: Ed Chen and Rea Dabelic, two members of the BioLegend Technical Team, take over the podcast this week to discuss Selman Waksman (the Father of Antibiotics), tuberculosis, and giving credit where its due.
Keywords: Selman Waksman, Albert Schatz, streptomycin, neomycin, antibiotics, Neosporin, tuberculosis, granulomas, macrophage, biolegend, immunology, mycobacterium tuberculosis, podcast, patents, inventions, royalties, tuberculin skin test, lab assistants, consumption, avastin, microbiology, birthday blog, controversy, Nobel prize Having difficulty playing this episode? Description: We welcome Chris Gould to discuss neuroscience, protein misfolding, aggregation, and prion-like proteins in neurodegenerative diseases. Keywords: neuroscience, tau, a-synuclein, alzheimer's disease, parkinson's disease, neuroinflammation, prions, Creutzfeldt-Jakob disease, mad cow disease, kuru, cannibalism, brain, aggregation, protein misfolding, blood brain barrier, lymphatic system, chris gould, biolegend, immunology, podcast, neurofibrillary tangles, lewy bodies, inclusion, Lou Gehrig's disease, ALS, amyotrophic lateral sclerosis, neurodegeneration, microglia Having difficulty playing this episode? Description: Neuroinflammation can be beneficial in some instances, but too much of it can cause any number of neurological diseases. Keywords: Kenya Cohane, neuroinflammation, neuroscience, alzheimer's disease, parkinson's disease, multiple sclerosis, tau protein, a-synuclein, aggregation, immunology, podcast, biolegend Having difficulty playing this episode? Description: Antibody therapies have become incredibly popular for the treatment of diseases, including cancer. Keywords: cancer, tumor, antibody therapy, therapeutics, immune checkpoints, PD1, PDL1, LAG3, TIM3, CD80, CD86, Galectin 9, MHC II, CTLA4, Pembrolizumab, Ipilimumab, Nivolumab, nanobody, melanoma, carcinoma, biolegend, science, podcast, merck, amgen Having difficulty playing this episode? Description: CRISPR is an amazing technology originally discovered in bacteria as a defense mechanism against invading foreign genetic material. Description: Despite our advances in science and technology, it seems like more and more people are outright denying scientific principles and concepts like evolution and climate change. Keywords: podcast, biolegend, immunology, biology, climate change, ted cruz, NASA, jim inholfe, brain, neuroscience, music, ignorance, science, education, ivory tower, spock, star trek, leonard nimoy, evolution, fluorine, fluoridination, fanta, Tourette Syndrome, nerdy, nerds, nerd, fandom Having difficulty playing this episode? Description: In this podcast, we discuss bacterial hot spots in New York, a brand new antibiotic found in dirt, telomeres and aging, and an interesting article published in 17 scientific journals about Cocoa Puffs. Keywords: podcast, podcasts, New York, subways, bacteria, antibiotics, MRSA, antibiotic resistance, telomeres, cocoa puffs, teixobactin, beer, alzheimer’s disease, parkinson’s disease, aging, BioLegend, immunology, biology, science, grad school, scientific journals Having difficulty playing this episode? Description: In this podcast, we take a look at how a lack of vaccinations has once again caused an outbreak of a once-controlled disease, the efficacy of the flu vaccine this year, and why people are clamoring to know if their food contains DNA. Keywords: podcast, science, measles, vaccinations, vaccines, anti-vaxxers, Jenny McCarthy, research, cures, Disney, Disneyland, outbreak, flu vaccine, influenza, flu, dna, food, GMO, genetically modified organism, antibiotics, virus, viruses Having difficulty playing this episode?
Description: In this podcast, we examine why it’s so hard to transition from animal research into human cures and Obama’s latest visit to the NIH. Keywords: podcast, president, Obama, Barack Obama, BioLegend, NIH, National Institutes of Health, science, Ebola, HIV, Human immunodeficiency virus, AIDS, acquired immune deficiency syndrome, translational models, animal models, translation, research, bench to bedside, cures, vaccines Having difficulty playing this episode? We examine increasing cases of diabetes and how finding the "secret sauce" for beta cells might fight this trend.
BioLegend is working with Sean Parker and the Parker Institute’s collaboration in fighting back against cancer. Recent studies have reported a link between Herpes Simplex Virus 1 (HSV-1) and increased AD risk.
This blog will cover the major apps provided by BioLegend relevant to research steps from conceptualization to discovery, as well as a few useful apps not from BioLegend. Look back at this year’s most popular posts and find out which blogs our writers enjoyed composing.
Our latest podcast invites guest Pascal Gagneux to discuss his thoughts on glycans, evolution, and sex cells! Learn what makes this virus dangerous and why some countries are advising women to avoid pregnancy. Although respiration is considered the more efficient pathway because it has more ATP output per molecule of pyruvate, rapidly-dividing cells sometimes choose fermentation instead. Almost 50 BioLegend employees took part is this fun race which supports awareness for local charities trying to bring about positive change in San Diego. By controlling key molecules involved in regulating the immune response, researchers have obtained very promising results in the treatment of certain cancers. Read this blog to learn more about Mazumdar-Shaw’s humble beginnings and how she built her empire by literally starting in her garage. Scientists would like to reanimate this virus to learn more about its origins and the evolution of giant viruses. We also cover recent research linking high-fat diets with a change in the gut microbiome and obesity-linked inflammation, as well as the role that leptin plays in the rewarding effects of exercise.
Immunotherapy is a groundbreaking option because it can hypothetically target cancer cells specifically while leaving healthy cells intact, which can decrease the number of adverse effects associated with current treatment options. Some may notice a modest decline in their mental abilities, including memory function, while some may develop neurodegenerative diseases as they age. Tune in to hear our guest Mohar Chattopadhyay discuss its symptoms, treatments, and research. Using bioinformatics methods, they reconstructed the evolutionary tree of AAV and made viruses that represent different branching points.


Resistance to anti-microbial drugs occurs naturally, however, the misuse of these drugs, among other factors, is helping the spread of multidrug resistant microbes. However, communication between the CNS and the periphery occurs through unknown mechanisms. The cause of this disease is unknown, and although there is presently no cure, there are some treatment options such as medication and surgery to manage its symptoms.
Learn more about neuroinflammation and the newly discovered central nervous system lymphatic system with our special guest, Kenya Cohane. They are highly similar to peripheral macrophages and respond to pathogens and injury by becoming activated.
But, how does this peer review work and why have so many controversies sprung up recently about this system? The Neuroinflammation page shows how neuronal injury can lead to immune infiltration, and how differential activation of microglia can be either neuroprotective or neurotoxic. This versatile system can accommodate your experimental needs, whether you are doing positive or negative selection.
In cancer, it may be beneficial to prevent interaction of "immune checkpoints", which can inactivate T cells. This time we contribute to science enrichment classes in elementary schools throughout San Diego. In this blog, we discuss the potential impact of sequencing or genotyping individuals and why the FDA temporarily shutdown one company for marketing their kit as a medical device. Quite often, they manage to subvert a highly evolved immune system and proliferate inside a host. It allows researchers to listen to important talks, collaborate, and see what companies have to offer. Researchers are now repurposing this for useful applications in like increasing crop size and treating diseases like HIV and cancer. With open source sharing of 3D models, anyone with access to a 3D printer can print tube racks, 96 well plates, gel combs, and many other things. We also take a look at some of the inner workings of the brain including synchronization, implanting false memories, and how it blocks distractions.
In this blog, we discuss one of the biggest scientific scandals in recent memory: The publication of high-profile stem cell papers in one of the most reputable journals that was riddled with errors, and, in at least a couple of spots, obvious data manipulation. Depending on the requirements of your assays, as well as your equipment at hand, you may need to use a colorimetric assay. This blog discusses the implications of red meat consumption in humans and the characterization Neu5Gc as a xeno-autoantigen capable of inducing low level inflammation leading to cancer. These are called plantibodies, and in fact, there are already companies developing therapeutic antibodies using them.
There we showcased some of our newly released products, such as LEGENDplex and newly aquired NeoClone antibodies.
Our blog examines possible causes, treatments, and mechanisms of action for food allergens. Keywords: BioLegend, science, podcast, podcasts, immunology, neuroscience, memory, alcohol, beer, neurons, ion channels, NMDA receptor, redox, oxidation, reduction, calcium, potassium, sodium, hippocampus, GIRK receptor, addiction, Karthik Bodhinathan, Stuart Lipton Having difficulty playing this episode?
And, we talk about Sean Parker's new $250 million grant to establish the Parker Institute for Cancer Immunotherapy. In this blog, we discuss a landmark case study, and human trial, in which gene editing was successfully used in the treatment of leukemia. As hard as it is to secure funding, prioritizing how to stay within the lab’s budget is an equally daunting task. The use of monoclonal antibodies against some of these molecules, called immune checkpoint receptors, have provided some answers and hope in the search for a cure. Tune in to hear our discussion on the release of an open-access journal that will publish ideas as well as data and results, and other exciting research on influenza infection. In this blog, read about adoptive cell transfer, the process of training and expanding a patient's own immune cells and placing it back into the patient to fight the cancer with their own cells.
Scientists are increasingly interested to understand the factors and mechanisms that may impact brain health. These viruses were used to circumvent detection by the immune system to successfully deliver genes to various mammalian tissues. This is a serious public health issue at the moment, and if we don’t act with energy, there can be hard consequences.
In this blog, we discuss a recent paper published in Nature that discovered that the CNS does, in fact, have a lymphatic system that can be used to communicate with immune cells in the periphery. Read our blog to learn more about Selman Waksman, his work in antibiotics, and the controversy over streptomycin. Read our blog to learn more about the correlation between the flu vaccine and narcolepsy, and the evidence to support or refute the hypothesis.
Read our blog to learn about the work being done to uncover how bacteria can influence the mental state. This blog discusses the blood-brain barrier, which can be compromised under certain conditions, leading to immune cell infiltration and chronic neuroinflammation. As part of their response, they secrete cytokines and chemokines, which help in the resolution of the inflammatory response. The page also features IHC reagents for detection of neuroinflammation and a list of our neuroinflammation products.
Learn more with our podcast about some of the more popular antibody and nanobody treatments. Read about BioLegend at IMMUNOLOGY 2015™ in this blog, and we’re excited for next year's AAI Annual Meeting! Check out our blog to learn how Joseph Lister turned it all around and why he is now known as "the father of modern surgery". In this post, we comment on the number of mechanisms that HIV, a retrovirus, has to escape the immune system.
Learn about BioLegend's involvement in scholarships, talks, and interesting facts about this year's host city, New Orleans. There's a battle brewing over the CRISPR patents with millions in funds (and profit) at stake. This allows for on-the-fly access to lab goods, and also nearly infinite customizability for lab supplies in your experiments. The fallout after the retraction of these papers just goes to show that scientific misconduct is not worth the risk.
Luckily, our immune system has also “learned” how to deal with most of these pathogens, so we can eliminate most of these infections. Read through our blog to learn more about the logistics of picking out the right animal for you. Read this blog to get an idea about how much it costs to run an academic research lab in the U.S.


BioLegend develops and manufactures world-class, cutting-edge immunological reagents for biomedical research, offered at an outstanding value. If you're able to score a perfect 100%, you'll win a goodie bag filled with BioLegend prizes.
But these cells are also known for their harmful roles in neurodegenerative diseases and brain injuries, such as Alzheimer’s and Parkinson’s disease.
In this post, we comment on a number of mechanisms that Salmonella has to escape the immune system. In this post, we comment on a number of mechanisms that Listeria has to escape the immune system. THESE VERY SAME ENFORCEMENT AGENCIES, WHO HAVE SWORN TO PROTECT AND SERVE, OUR COUNTRY, AND CITIZENS ,ARE BUT SOME, OF THE CORRUPT,GREEDY TRAITORS .ENGAGED IN THE TYRANNY AND TORTURE. The school district has moved to a biometric identification program, saying students will no longer have to use an ID card to buy lunch.A  BIOMETRICS TO TRACK YOUR KIDS!!!!!i»?i»?A TARGETED INDIVIDUALS, THE GREEDY CRIMINALS ARE NOW CONDONING THEIR TECH!
Paul Weindling, history of medicine professor at Oxford Brookes University, describes his search for the lost victims of Nazi experiments.
The chairman of the board at ESL a€” then proprietor of the desert wasteland in Nevada known as a€?Area 51a€? a€” was William Perry, who would be appointed secretary of defense several years later. EUCACH.ORG PanelIn a 2-hour wide-ranging Panel with Alfred Lambremont Webre on the Transhumanist Agenda, Magnus Olsson, Dr.
Henning Witte, and Melanie Vritschan, three experts from the European Coalition Against Covert Harassment, revealed recent technological advances in human robotization and nano implant technologies, and an acceleration of what Melanie Vritschan characterized as a a€?global enslavement programa€?.Shift from electromagnetic to scalar wavesThese technologies have now shifted from electromagnetic wave to scalar waves and use super quantum computers in the quantum cloud to control a€?pipesa€? a reference to the brains of humans that have been taken over via DNA, via implants that can be breathed can breach the blood-brain barrier and then controlled via scalar waved on a super-grid. Eventually, such 'subvocal speech' systems could be used in spacesuits, in noisy places like airport towers to capture air-traffic controller commands, or even in traditional voice-recognition programs to increase accuracy, according to NASA scientists."What is analyzed is silent, or sub auditory, speech, such as when a person silently reads or talks to himself," said Chuck Jorgensen, a scientist whose team is developing silent, subvocal speech recognition at NASA Ames Research Center in California's Silicon Valley.
We numbered the columns and rows, and we could identify each letter with a pair of single-digit numbers," Jorgensen said.
People in noisy conditions could use the system when privacy is needed, such as during telephone conversations on buses or trains, according to scientists."An expanded muscle-control system could help injured astronauts control machines.
If an astronaut is suffering from muscle weakness due to a long stint in microgravity, the astronaut could send signals to software that would assist with landings on Mars or the Earth, for example," Jorgensen explained. These are processed to remove noise, and then we process them to see useful parts of the signals to show one word from another," Jorgensen said.After the signals are amplified, computer software 'reads' the signals to recognize each word and sound.
Our Research and Development Division has been in contact with the Federal Bureau of Prisons, the California Department of Corrections, the Texas Department of Public Safety, and the Massachusetts Department of Correction to run limited trials of the 2020 neural chip implant. We have established representatives of our interests in both management and institutional level positions within these departments. Federal regulations do not yet permit testing of implants on prisoners, but we have entered nto contractual agreements with privatized health care professionals and specified correctional personnel to do limited testing of our products. We need, however, to expand our testing to research how effective the 2020 neural chip implant performs in those identified as the most aggressive in our society. In California, several prisoners were identified as members of the security threat group, EME, or Mexican Mafia. They were brought to the health services unit at Pelican Bay and tranquilized with advanced sedatives developed by our Cambridge,Massachussetts laboratories. The results of implants on 8 prisoners yielded the following results: a€?Implants served as surveillance monitoring device for threat group activity. However, during that period substantial data was gathered by our research and development team which suggests that the implants exceed expected results. One of the major concerns of Security and the R & D team was that the test subject would discover the chemial imbalance during the initial adjustment period and the test would have to be scurbbed. However, due to advanced technological developments in the sedatives administered, the 48 hour adjustment period can be attributed t prescription medication given to the test subjects after the implant procedure. One of the concerns raised by R & D was the cause of the bleeding and how to eliminate that problem. Unexplained bleeding might cause the subject to inquire further about his "routine" visit to the infirmary or health care facility. Security officials now know several strategies employed by the EME that facilitate the transmission of illegal drugs and weapons into their correctional facilities. One intelligence officier remarked that while they cannot use the informaiton that have in a court of law that they now know who to watch and what outside "connections" they have. The prison at Soledad is now considering transferring three subjects to Vacaville wher we have ongoing implant reserach. Our technicians have promised that they can do three 2020 neural chip implants in less than an hour.
Soledad officials hope to collect information from the trio to bring a 14 month investigation into drug trafficking by correctional officers to a close. Essentially, the implants make the unsuspecting prisoner a walking-talking recorder of every event he comes into contact with. There are only five intelligence officers and the Commisoner of Corrections who actually know the full scope of the implant testing. In Massachusetts, the Department of Corrections has already entered into high level discussion about releasing certain offenders to the community with the 2020 neural chip implants. Our people are not altogether against the idea, however, attorneys for Intelli-Connection have advised against implant technology outside strick control settings. While we have a strong lobby in the Congress and various state legislatures favoring our product, we must proceed with the utmost caution on uncontrolled use of the 2020 neural chip. If the chip were discovered in use not authorized by law and the procedure traced to us we could not endure for long the resulting publicity and liability payments. Massachusetts officials have developed an intelligence branch from their Fugitive Task Force Squad that would do limited test runs under tight controls with the pre-release subjects. Correctons officials have dubbed these poetnetial test subjects "the insurance group." (the name derives from the concept that the 2020 implant insures compliance with the law and allows officials to detect misconduct or violations without question) A retired police detective from Charlestown, Massachusetts, now with the intelligence unit has asked us to consider using the 2020 neural chip on hard core felons suspected of bank and armored car robbery. He stated, "Charlestown would never be the same, we'd finally know what was happening before they knew what was happening." We will continue to explore community uses of the 2020 chip, but our company rep will be attached to all law enforcement operations with an extraction crrew that can be on-site in 2 hours from anywhere at anytime.
We have an Intelli-Connection discussion group who is meeting with the Director of Security at Florence, Colorado's federal super maximum security unit. The initial discussions with the Director have been promising and we hope to have an R & D unit at this important facilitly within the next six months. Napolitano insisted that the department was not planning on engaging in any form of ideological profiling. I will tell him face-to-face that we honor veterans at DHS and employ thousands across the department, up to and including the Deputy Secretary," Ms. Steve Buyer of Indiana, the ranking Republican on the House Committee on Veterans' Affairs, called it "inconceivable" that the Obama administration would categorize veterans as a potential threat.



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