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admin | Category: Erective Dysfunction 2016 | 10.02.2015
Graves’ disease is a disorder of the immune system that causes the thyroid gland to become overactive. Goiter — Goiter is a swelling in the lower front portion of the neck caused by an enlarged thyroid gland.
Your doctor will look for physical evidence of Graves’ disease, including goiter, eye signs and skin signs. During your physical examination, your doctor will feel your thyroid for abnormal nodules (lumps) and to see if it is enlarged. Your doctor will order blood tests to determine whether your thyroid is producing and releasing too much hormone. Symptoms of palpitations, increased heart rate, tremor and nervousness are treated with a beta-blocker medication such as propanolol (Inderal). To stop the thyroid from producing too much hormone, there are three possible treatments: antithyroid medications, radioactive iodine, and surgery. Graves’ disease is most often treated with the anti-thyroid drug methimazole (Tapazole, generic versions).
Patients with eye signs of Graves’ disease may be given eye drops to keep the eyes moist and tinted eyeglasses to protect the eyes from sun, wind and dust.
Also call your doctor if you develop swelling or skin changes in your feet or lower legs, or if you notice a change in your eye appearance or eye function. Many patients remain well after a single course of anti-thyroid drugs, but recurrence can happen at any time. Thyroid acropachy: report of 40 patients treated at a single institution in a 26-year period. If you believe that any content appearing on this site infringes on your copyright, please let me know right away.
It is a condition that happens because of an excess secretion of thyroxin produced by your thyroid gland.
People who are suffering from Graves Disease will usually show similar symptoms that people with hyperthyroidism are showing.
In addition to the general symptoms there are some that are very distinctive to Graves Disease.
When a person has an autoimmune disease such as Graves Disease the immune system will produce antibodies that will work against the tissues of the body itself instead of producing antibodies to destroy any foreign bodies. They have found no particular gene that triggers this malfunction but some scientist believe that there are certain people who just inherit an immune system that produces these antibodies that attack your healthy cells. Autoimmune diseases—if a person already has an autoimmune disease such as Type 1 diabetes or rheumatoid arthritis can also get Graves Disease. The most effective treatment used today for Graves Disease was discovered many decades ago.
Having Graves Disease can be a major health concern for some pregnant women and can be a high risk complication during pregnancy.


Curing your hypothyroidism by taking a medication that is safe to take during pregnancy called propylthiouracil (PTU) prescribed by your doctor. Surgery – this treatment is reserved for women who need a high dose of medication to help control their elevated levels of thyroid hormones or is allergic to the medication. Use an over-the-counter ointment or cream that contains hydrocortisone to help with the redness and swelling of your skin. It is possible that the abnormal production of immunoglobulins is triggered by some unknown factor in the environment, and the immune system fails to stop this overproduction because of an inherited defect. In older people, particularly people with heart disease, the disease may cause heart failure or heart-related chest pain called angina. He or she also will ask you about recent weight loss, nervousness, tremors (shakes), increased sweating, palpitations, unusually frequent bowel movements, menstrual irregularities and whether you feel hot all the time.
He or she also may use a stethoscope to listen for signs of abnormal blood flow near your thyroid gland. If your doctor is concerned about potential eye problems, he or she may order a computed tomography (CT) scan or magnetic resonance imaging (MRI) scan of your eyes. Symptoms related to the high levels of circulating thyroid hormone will quickly improve with medications such as beta blockers and tranquilizers. For anxiety and insomnia, your doctor may prescribe diazepam (Valium), lorazepam (Ativan) or a similar medication. Most specialists recommend a large enough dose to completely stop the thyroid from producing thyroid hormone.
However, people with very large goiters are less likely to respond well to anti-thyroid medication or radioactive iodine, and may have a better outcome if most of the thyroid gland is removed surgically (called subtotal thyroidectomy). In people with severe eye symptoms, glucocorticoid medications may be necessary, either alone or together with radiation treatments to the muscles that control eye movement. Radioactive iodide is very effective, but often results in abnormally low levels of thyroid hormones (hypothyroidism). He also had exophthalmos in both eyes, heat intolerance, slight tremor, diarrhea, and unintentional weight loss.Physical examination revealed violaceous to yellow nodules on the anterior surfaces of the bilateral lower legs (see accompanying figure) that were boggy and nontender. A person viewing it online may make one printout of the material and may use that printout only for his or her personal, non-commercial reference.
It is considered an autoimmune disease and one of the most common autoimmune diseases today. With Graves Disease the antibodies that are produced will bind themselves to the surface of your thyroid cells. There are many different treatments that can be used to treat this condition but if you are pregnant, treatment differs.
If you are diagnosed with Graves Disease if would not be advisable to use general treatments because it can cause an adverse effect on the normal procedure of delivering the baby and on the developing fetus.
In other parts of your body, your doctor will check for additional signs of hyperthyroidism, including fast heart rate, irregular heart rhythm, hand tremor, fast reflexes when tendons are tapped with a soft hammer, and bulging eyes.


It takes several weeks for the action of anti-thyroid medications to lower thyroid blood levels toward normal.
Skin symptoms of Graves’ disease may be treated with glucocorticoid creams and ointments. This material may not otherwise be downloaded, copied, printed, stored, transmitted or reproduced in any medium, whether now known or later invented, except as authorized in writing by the AAFP. This condition leads to hyperthyroidism, which is when your thyroid glad is overactive and stimulates your metabolism which in turn can cause a person to tremble, have an increased heart beat, have a high level of perspiration, etc. Normally only a small percentage of people with Graves Disease will suffer from these types of eye problems. Anti-thyroid medication is continued for at least one year unless another treatment is used.
However, it should only be used in patients who cannot tolerate methimazole and in women just before and during their first trimester of pregnancy. Because people who receive radioactive iodine therapy temporarily store a small amount of radiation in their thyroid, they need to avoid prolonged contact with pregnant women and children for several days following treatment. Once thyroid hormone levels have reached normal, you and your doctor can decide whether to continue daily anti-thyroid medication or to choose radioactive iodine treatment. Radioactive iodine is concentrated in breast milk and women must stop breast feeding if they choose this therapy. Graves Disease can affect anyone but you will find it mostly in elderly people, children, and infants.
It is still not known exactly what causes your immune system to malfunction and cause this condition but there are some factors that are considered to possibly cause the malfunction in your immune system.
In addition it is more prominent in women than men with the rate being as much as seven times higher for woman. Graves disease is an autoimmune disorder that causes the excessive release of thyroid hormone through the action of thyrotropin receptor antibodies. It usually manifests as indurated nodules or plaques that are flesh-colored to violaceous.3 A peau d'orange appearance is possible because of the prominence of hair follicles.
Although the condition is most often idiopathic or postinfectious, assessment for an underlying systemic disease or offending medication may be warranted. Possible triggers include sulfonamides, oral contraceptives, pregnancy, sarcoidosis, streptococcal pharyngitis, tuberculosis, and ulcerative colitis.8Lichen myxedematosus (papular mucinosis) is a rare inflammatory disease of fibroblastic proliferation and dermal mucin deposition. It produces a fleshy, papular skin eruption that may coalesce into plaques, most commonly on the face, dorsal hands, and extensor surface of the extremities.9 The condition is usually associated with monoclonal gammopathy.



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