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16.05.2015
He asked another Pfizer chemist, Willard Welch, to synthesize some previously unexplored tametraline derivatives. Welch then prepared stereoisomers of this compound, which were tested in vivo by animal behavioral scientist Albert Weissman. Over a decade into the industry, Nathan continues to be progressive and primitive in his approach. I wanted to work in an industry that allowed me to work with myriad people on a daily basis.
The next time you’re in class, look around at the different ages, levels of fitness, and abilities all working in the same room at the same time.
The moment when you see the shift from someone as their former self to their more confident, newer self. AFS is great for guys of any age who need to shed a few pounds of fat, increase lean muscle, and just feel healthier and better….It is an awesome work out, great trainers, and a very professional establishment – I recommend it to anyone who is interested in being healthier, looking better, and feeling stronger. The staff at AFS are always with me to help correct my technique so I don’t injure myself both in the gym, and when I am working out alone…I know they are only an email or phone call away from getting the help I need. With AFS Group Strength Training, my upper body has physically become defined and toned more than I could have imagined. I had recently given birth and did not want to sit and wait to slowly lose the baby weight by getting a workout in here and there. I strongly believe in Applied Fitness Solutions approach in shifting your body into an accelerated fat burning state.
I had been working out at AFS for about 6 months and had reached a plateau in my weight loss. After one meeting and breaking down his system I realized that his program was completely different than anything that I have tried or even heard of….
I never thought of myself as a ‘weightlifter,’ but my group strength training experience at AFS has been amazing. I was interviewed yesterday by a researcher at Harvard's Kennedy School of Government for a case study on the role weblogs played in the downfall of Trent Lott. Another cool thing about driving to NY is when you get close enough to see big green Interstate highway signs that say New York City.
We're getting close to June 14, when, last year, to people who read this site I just disappeared. Ed Cone links to a story from Mark Tosczak, a NY Times stringer, on getting credit for his work. I've given Tim Bray his share of grief, but in this piece about the state of CSS, he nails it. Four years ago: "Salon (justifiably) brags that they've matured to the point where they could send a reporter to Yugoslavia.
Cory Doctorow reports on an Apple update that makes it so that iTunes can only stream to people on the same subnet.
On Thursday I'm giving a keynote at the Open Source Content Management conference, or OSCOM. There's been a bit of discussion about my last DaveNet piece, mostly users talking about what they're willing to pay, as if they have all the power. The power of the software developer not to develop is largely silent, so people don't consider it. A professional software organization for a well-supported product has 10-20 people, maybe as many as 30 to 40. Let's say you spend 100 hours a year using a piece of software and assume your time is worth $50 per hour. I don't know if this means anything but there are no stories on Google News about Colorado Governor Bill Owens's veto of the state "Super-DMCA" law. Robert Wiener writes to say that searching for Colorado and veto gets a bunch of hits on Google.
Speaking of Google, I was kind of bored and wanted to see how my investment in John Doerr was doing, so I fired up Google, and lo and behold, my story is #3. I wonder why some weblogs so openly say things that are just plain wrong, that are so easily refuted, without presenting the opposing data, or even suggesting it might exist with a disclaimer like imho, or ymmv, or ianal. Most places I don't expect journalism, but some places I do, and they disappoint often enough to make it noteworthy.
One thread on a respected blogger's site gives the whole weblog tools market to one of the companies. BBC: "Jodi Plumb, 15, from Mansfield, Nottinghamshire, was horrified to discover an entire site had been created to insult and threaten her. Ellen Ullman: "To listen to Mr Engelbart that day almost five years ago was to realize that the computer industry, when it started, was not simply about becoming a chief executive or retiring on stock options at 35. Sjoerd: "It is noisy outside, and 2 riot police cars are racing by, because ADO Den Haag has won the 1st division soccer leage.
Flying over Boston or NY it's astonishing how much real estate is used to house dead people.
I was sitting in a law school cafeteria yesterday thinking how far away I was from the threat of terrorism.
Ben Edelman, a Harvard Law student and fellow at Berkman, has been studying Gator, one of the leading advertising servers. Marketing Profs: "Blogs offer the human voice, which can be loud, controversial, and even wacky.
A few people have suggested asking people to send Google API keys they aren't using and rotate them to work around the fatal flaw.
BTW, some people said the Nikon took better pics than the Sony I use now, but I don't think so. Evan Hansen: "Paralyzed by fears of piracy, the record labels have taken years to get their act together for online distribution. Bloki is "a Web site on which you can create Web pages, right in your browser, with no additional software required. Microsoft's decision to support RSS without arguing over what it is looks smarter every day.
Scoble, who works at Microsoft now, says he likes using a desktop app to write his internal weblog.
Disclaimer: I've been trying to work on weblog-tool compatibility issues with Google for the last few weeks. The program being intensive in voice in movement pushed Nathan to study and develop himself from a physical perspective as relative to performance.
It’s the pursuit of why and how that propels him to motivate, inspire, teach, and continue learning as the science, population, and progression are in flux. My clothes are fitting the best since giving birth to my first child and I’m on my way to getting back to my smallest size ever… I would recommend this program to anyone that is willing to work in order to see results quickly and safely! I’ve lost the body fat, added muscle, and after a year of training to run again, I recently completed my first marathon in 11 years. I had been working out 4-5 days a week for the past year and a half and was not able to get the results I wanted. I was looking for an additional way to increase muscle definition and tone in order to improve my overall physique and strength.
Whether “in shape” means losing 10lbs or 150lbs, or setting a new marathon PR, AFS has the systems and the science that will get you there. Homeopathic individualized medicines versus fluoxetine for moderate to severe depression: double-blind, randomized non-inferiority trial.
There's something for everyone, whether you like Bill Gates or Richard Stallman, or neither. Bragg's colleagues on the national staff had exchanged phone calls and e-mail messages, angered by comments from Mr. As OSCOM starts, the issues of interop betw content management tools is very hot in the open source world thanks to work by Paul Everitt and Gregor Rothfuss.
Using my wingy-dingy new search engine, I found a great reference, a mini-article entitled Oh Lieberman, which should have been entitled Oy Lieberman. Sure the original author may toil at a money-losing labor-of-love long past the point where it has been proven not to be viable, but what about the people he or she is not hiring, the manual writers, testers, more programmers, a sales person, a marketing person perhaps, to work on ease of use and to keep the website current. So when you hear yourself complaining about software quality, think about how much money the developer of the product has to fully support it.
They link to one press release from the Music Indistry (sic) News Network commending the governor for the veto.
BTW, I wasn't thinking Google might have been holding back, I was thinking the newspapers were. Microsoft's developer program was kaput, everyone who was anyone wanted to develop for the Web, and that led them to Netscape and Sun, and away from Microsoft.
Being in a dead software market is no fun, even when you haven't signed on with the dying platform vendor. He's got a Web app that simulates a Gator client, and sends messages back to Gator asking for ads to display on certain sites.
Somehow MS has taught its people not to care about issues that are not related to success or failure of products.
I've noticed that it colors how I think about them, not in a positive way, and felt I should disclose that, since I write about them here on Scripting News. Arch Gen Psychiatry -- Early Coadministration of Clonazepam With Sertraline for Panic Disorder, July 2001, Goddard et al.
It was this matriculation toward a more physical existence that was the impetus for further study and pursuit. Mentally, strength training has helped to build confidence in myself through self discipline and a strong work ethic allowing me to meet goals and challenges I never thought could be accomplished not only in the gym, but also in my personal life. The strength training class provides me with my own personalized workout and a knowledgeable staff member always there to assist. After joining AFS I started to see results in the 2nd week and by the end of my 6th week I met the short-term body composition goals set up for me. I have a set number of calories that I may have in a day and in does not matter what type of food I consume….The workouts are hard but manageable. Each workout is individually tailored to my fitness goals and is both challenging and rewarding. Ubiratan Cardinalli Adler, UNIFESP (Federal University of SA?o Paulo, Brazil), Av Rouxinol, 1041 cj. To me it was the day I quit smoking, and also the day I checked into the hospital (when I wrote that post I didn't know for sure I'd have to go into the hospital, but I wasn't surprised when I did).
In my talk yesterday I said this was a species of software developer with a lot of power, a beast of the 80s, extinct this century. Before that I told the story of how XML-RPC came to be, and how Eric Raymond liked it so much. By making my position public about the equivalent issues in the weblog world, I will be joining with them in requesting that we put aside our differences (I'm not sure there are any) and establish a set of principles on how we build from here. Financiers invested, and gave back to the university so the next generation of technology entrepreneurs could be educated, nutured and launched." It wasn't clear that financiers invested in the companies started by the students, not in the work done at the universities. He met up with the proprietor of that site at a place in NYC called Alt.Coffee on Avenue A in Manhattan. How about a couple of tech support people (so they can take a vacation once in a while, it's a tough job).
When you buy a new computer you probably pay a few hundred dollars for software, most of it going to Microsoft. How much self-respect is there in paying nothing for software that leverages so much of your time?
So even if you don't want to pay for the time-leverage software delivers, would you pay money to keep your money safe? Is it based on features, or any deep understanding of how the products work, or the economics of the market?
Hosting is a tricky business, as we found out, there are ISPs who now host MT sites that must somehow be included in their plans, yet there seems to be no mention of them in the FAQ.
Here's how I like to look at it -- formats and protocols are tools, details; the important thing is functionality delivered to users. This is where the road splits and Nathan graduated but pursued a career in the fitness industry.
The way AFS has designed the program, a 20 year old and a 65 year old can work out in the same class and achieve their own goals. That's all there is to it, except when you really want to get it you should let just a hint of an R back.
Shortly after my reappearance, Seth Dillingham said something really nice and very memorable.
Apparently he went over his allotted time, I wanted to ask him to comment on the opportunities for open source projects to integrate with commercial software.
I polished my skills as a user, and watched other people learn weblogs, saw what they got, and didn't. Then I hazarded a guess that if Eric had dinner with Bob Atkinson, one of the co-designers of XML-RPC, that they'd agree on a lot, and probably enjoy each others' company, even though Bob is a senior guy at (you guessed it) Microsoft.
I've tried to explain the issues in non-technical terms, yet of course as soon as words like APIs and XML appear a lot of ordinary people tune out.
Some of them are great writers and have passion for the truth and aren't serving the same masters that the bigtimes at WSJ, NYT and CNN. It's about a 20-minute drive to the office, not as convenient as living in Cambridge, but very sweet.
If you pay nothing for software, you probably won't die from it, but you may lose data, you're virtually certain to waste time, and at some point, money. I have data that contradicts theirs, fairly superficial stuff -- why, on investigation didn't they uncover it? If there are any busdev people I need to talk with at Google, I guess now's the time to do that.
He is certified through the National Academy of Sports Medicine in addition to being a Certified Functional Movement Specialist.
He has taken this stance with professional athletes, Division 1 athletes, Euro-League Basketball Players, pregnant moms, and everyone in between.
There is a need for large-scale longitudinal data on treatment utilization and outcomes, stress, emotion, and pain.
Also, reading the highway signs I kept seeing Oxford, which I wanted to write as a hex number: oXF08D.
And for sure, on May 31, 2002 I had chest pain, and was in denial on how sick I really was.


I asked other people for ideas of what made weblogs different from professional pubs and Wikis. They still are, but after SOAP and XML-RPC they could just as easily be running on a server farm.
And most of them don't have websites, yet, largely because it is too complicated and expensive to have one.
And if you pay $10 or $20 to use a piece of software, the software isn't paid for if the software isn't generating enough money to be fully supported or developed. Why don't a small number of users of the popular weblog tools work together to create an authoritative review of the category and show us how the products compare. It takes better pictures than the Nikon if I actually have it with me when I see something photo-worthy. Unfortunately I don't have any money to pay them for this, but I'm afraid that's what they're going to want to talk about.
You can certainly feel good about giving the money, but you're probably not going to get what you want or think you deserve in the way of support or upgrades for that kind of money.
I'm working on a taxonomy of weblogs for the two conferences I'm keynoting in the next two weeks.You can start there if you want but you probably don't need my help.
Nathan is currently pursuing a Masters of Psychology with an emphasis in Sport and Performance. Randomized long-term trial of camel milk as an adjunct to insulin therapy in type-1 diabetes. WE guarantee that our prices are much lower than the prices cited as VALUE PRICES ofA A  Healthcare Bluebook for Chicago areas. That's what I liked the most about Ringo, he needed a little help from his friends, and he appreciated it too. If you have a pain inside your chest where your heart is, go to see a doctor now, don't think you can exercise your way out of the corner. In other words, I did something rather unlike a weblog to try to get to the core of what one is. And get this -- this isn't just for Radio users, we created an open system that anyone can ping. The first hit took me to a guy about the right age, living in about the right place, but on further inspection I noted that (gullp) he died.
Patients are recruited from web sites for patient advocacy and health enhancement programs. Since there's no year on it, it's impossible to know if it's the Mitchell Stern I knew as a kid.
Therefore this long-term study was undertaken to assess the efficacy, safety and acceptability of camel milk as an adjunct to insulin therapy in type 1 diabetic patients.
Methods: In this 2-year randomized clinical parallel design study, 24 patients with type 1 diabetes were enrolled and divided in 2 groups.
Group I (n=12) received usual care (ie, diet, exercise, and insulin), and group II (n=12) received 500 mL camel milk in addition to diet, exercise, and insulin.
Here I sit 4 hours by car from NY, if I want a good pizza, I have to go there, they don't make it here.
Think of all the bandwidth that's wasted by search engines looking for changes on pages that never change. Previous studies have found that between 30% and 60% of pediatric neurology patients have used CAM at some point in their lives.
Whereas, the effect of vitamin C on conventional photodynamic therapy (PDT) of tumor cells has been documented, the mechanism of vitamin C induced increase in tumor cell response to PDT is unclear.
In this report we demonstrate the presence of vitamin C during photo-oxidation of MC540 significantly increases its apoptotic activity in tumor cells. Interestingly, we observed that the presence of vitamin C during photo-oxidation of MC540 only and not its addition to a prior photo-exposed mixture to MC540 is critical for its enhanced sensitivity. These findings provide impetus to the approach in developing ROS generating small molecule compounds with potent apoptosis inducing activity. These data could have implications in the use of vitamin C in photo-sensitizer-mediated reactions with the view to favorably tailoring the cancer cell milieu for efficient apoptotic execution.
Many patients are still not discussing their CAM use with their doctors and are using CAM alongside their conventional medicines, thereby increasing the likelihood for potential interactions. One limitation of this study is that our ability to determine between-site differences is limited by the difference in sample size. Electrodermal measures as clinical markers: Jing-point electrical impedance in adolescent women with chronic pelvic pain.
Consequently, skin electrical measures at Jing points are commonly obtained and interpreted for diagnostic purposes. Denise Adams, University of Alberta, 1047 RTF Building, University of Alberta, Edmonton, AB, T6G 2E1, Canada. The objective of this study is to determine whether electrodermal measures at Jing-points are associated with clinical outcomes in adolescents with chronic pelvic pain in a randomized, sham-controlled acupuncture trial. Methods: We recruited 18 adolescent women aged 13 to 22 years of age suffering from chronic pelvic pain and laparoscopically diagnosed with Stage I-III endometriosis. Using a Hibiki-7 device, normalized electrical impedance values were obtained at all 24 Jing-points for each treatment session.
Phase II: CAM research networks in Canada and the US will notify CAM providers of this study, so they may alert patients. Left-right asymmetry and measures for statistical dispersion (standard deviation and Gini coefficient) of Jing-point impedance values were calculated. Parents or legal guardians may self-identify and reply on behalf of patients under 18 year of age if they meet the criteria for Phase I. With a generalized estimating equation method, we evaluated the association between the electrodermal-derived measures and clinical outcomes while accounting for treatment designation and time. Phase III: The methods for phase II were utilized but CAM associations and training organizations were substituted for CAM research networks. The majority of the cases involved the use of Traditional Chinese Medicine to improve quality of life. Preliminary analyses indicate that, over time, subjects in the active acupuncture arm were more likely to have reduced left-right asymmetry and statistical dispersion of Jing-point measures compared to subjects in the sham-control arm. Further analyses with multivariable models will be performed to assess whether this difference is statistically significant for each electrodermal measure. The chiropractic care of children with otitis media: a systematic review of the literature utilizing whole systems research evaluation and meta-synthesis. Joel Alcantara, International Chiropractic Pediatric Association, 327 N Middletown Rd, Media, PA 19063.
Key words were otitis media and related words (ie, acute otitis media, otitis media with effusion, ear infections, etc) AND chiropractic.
A narrative review of the literature was performed and augmented with a meta-synthesis of the literature with a focus on chiropractic management and the application of a whole systems research (WSR) evaluation. Results: Our systematic review revealed 20 articles consisting of 6 case reports, 5 case series, 1 retrospective cohort, 2 prospective cohorts, 2 reviews of the literature, 2 commentaries, 1 survey study and 1 prospective, parallel-group, observer-blinded, randomized feasibility study.
Due to the lack of higher-level research design, a meta-analysis of the literature was not possible. This included the use of otoscopy and tympanogram to provide objective pretreatment and comparative outcome measures.
Eighty-nine percent of respondents reported treating pediatric patients; patients under the age of 17 made up 12% of chiropractic and 20% of both naturopathic and osteopathic patients. Activator, Gonstead, Toftness, Chiropractic Biophysics, and Diversified Techniques were utilized with an emphasis on the upper cervical spine (the C1 or C2 vertebral bodies). Approximately two-thirds of both osteopaths and naturopaths disagree or strongly disagree that immunizations are safe compared to one-third of chiropractors.
One paper described utilization of cranial technique, 2 papers described a dietary intervention, and 2 papers utilized soft-tissue massage to augment spinal manipulative therapy. Fifteen studies were amenable to the WSR evaluation resulting in a score of 7.06 from a maximum of 11.
The immunizations of most concern to the 3 professions included MMR, varicella, influenza, DPTP, and hepatitis. The most common reasons for concern were related to safety, including that vaccines may contain dangerous ingredients, may produce side effects, and may be linked to future problems such as neurological damage.
Conclusion: This systematic review highlights the need for more higher-level research designs in addition to incorporating new methodologies (ie, whole systems research) reflective of the holistic and vitalistic clinical and theoretical framework of chiropractic. The chiropractic care of children with enuresis: a systematic review of the literature utilizing whole systems research evaluation. Significantly more naturopaths advised parents against vaccinations (27%), compared to 10% of chiropractors, and 12% of osteopaths (P=.0002).
Joel Alcantara, International Chiropractic Pediatric Association, 327 North Middletown Rd, Media, PA 19063. There was no significant difference between groups for those advising parents in favor of vaccinations (15% C, 14% N, 6% O) (P=.1143).
Key words were enuresis, nocturnal enuresis, bedwetting as well as related words AND chiropractic. A narrative review of the literature was performed and augmented with an evaluation using WSR evaluation. Results: Our systematic review revealed 7 articles meeting the eligibility criteria for review. Four of the 7 papers involve case reports describing the care of children aged 8 to 14 years with primary complaints of nocturnal enuresis. Spinal manipulative therapy involved the use of Toggle recoil, Sacro-Occipital Technique, Activator Methods, Gonstead Technique, and Diversified Technique to address primarily segmental dysfunctions in the lumbosacral spine. We conducted a systematic review to assess the nature and severity of adverse events associated with pediatric acupuncture.
A large prospective cohort study (N=171) demonstrated improvement in wet nights per week from baseline following 2 weeks of care. In a randomized clinical trial, within-group comparison of pretreatment and comparative rates of enuresis subjects demonstrated an improvement.
However, the study was fraught with research design issues such as randomization and biostatistics. Six of the 7 studies were amenable to WSR evaluation and resulted in a scoring of 7.33 from a maximum possible score of 11 points.
One reviewer screened all articles, while the second reviewed all excluded articles to ensure that no article was inappropriately excluded. Full articles of potentially relevant references were retrieved and assessed by two independent reviewers.
The use of Whole Systems Research provides promise in contributing to evidence-based practice and reflects the holistic and vitalistic chiropractic approach to patient care. Results: Seven thousand, two hundred sixty-two potentially relevant articles were identified. Eleven of these studies included adults as the majority of patients; for these studies the age of the patient experiencing the adverse event was never reported. Most of the adverse events that have been identified in children were mild and included pain, bruising, and worsening of symptoms. The few adverse events rated as moderate or serious included one pneumothorax, 2 infections, and 2 cases of complications from needles left in the body.
Methods: This study was approved by the Institutional Review Board of Life University (Atlanta, Georgia).
A 26-item questionnaire was sent to 9000 subscribers of an online newsletter from Midwifery Today Magazine. The first domain identified demographics (midwife credentials, age, years in practice, and place of practice). The second domain queried participants regarding their formal and postgraduate training on the subject of chiropractic.
The third domain attempted to identify their experience (ie, positive or negative experience) with chiropractic personally and professionally as it pertains to pregnancy and infant care.
The fourth domain asked their opinion about the safety of chiropractic care for pregnant and pediatric patients. The fifth domain surveyed their knowledge regarding the scope of practice of chiropractic for pregnant and pediatric patients. The respondent ranged in age from 41 to 50 years with practice experience ranging from 6 to 10 years. With respect to their training on chiropractic, 31% (n=57) reported receiving formal education (ie, during midwifery education) on the subject of chiropractic. Fifty-five of the 157 who did not indicated receiving some education on chiropractic through continuing education seminars. With respect to the midwife responders’ experience with chiropractic, 95% (n=176) admitted to making a professional referral to a chiropractor with 73% (n=137) having referred an infant to a chiropractor. Ninety-two percent (n=171) reported being chiropractic patients with another 58% (n=124) presenting their child for chiropractic care.
Over 90% indicated experiencing a positive experience as patients and with their child’s care. All of the respondents perceived chiropractic was safe for pregnant patients, while only 97% considered chiropractic safe for children.
An overwhelming majority of the responders (98%) indicated that chiropractors work with birth professionals, while 92% indicated that they were knowledgeable about the role of chiropractic in prenatal care. Lastly, 75% indicated interest in learning more about chiropractic, with 86% wanting more evidence-based practice chiropractic. From the 809 articles reviewed, 18 articles met the full inclusion criteria and proceeded to data extraction. Identified adverse events include local pain or soreness, swelling, mild fevers, and skin rashes. Thus far, the majority of adverse events reported have been mild with few moderate or serious adverse events occurring in pediatric patients. Total weight and body composition changes in response to weight reduction diets of varied protein content in midlife women.
Age-related changes in body composition for women include loss of lean mass and gains in total weight, fat mass and central fat deposition. There is growing evidence that diets with low-to-moderate carbohydrate and fat content and increased levels of high-quality protein are effective for weight loss.
Greater subjective satiety is reported by subjects following test meals containing whey protein compared to other protein sources.
The beneficial effects of whey protein on satiety, thermogenesis, and lean body mass protection suggest that whey may be a preferred protein source for weight loss treatment.


The specific aims of this study are to assess weight loss in subjects receiving energy-reduced dietary regimens and to evaluate parameters of weight and body mass change between the 3 treatment groups.
Study Design: We are conducting a randomized, controlled pilot feeding study to evaluate the effect of different dietary protein sources on weight loss. Endpoint measures include body weight and body composition data obtained at baseline and at 8 weeks for dietary treatment. The HP diet and the WP diet produced greater total fat loss and less total lean tissue loss than the CD. Conclusions: Preliminary data shows that across treatment groups, the high-protein diets conserved lean tissue and promoted reduction of fat tissue. Trials investigating TCM must be conducted with increased methodological rigor to be of value in evaluations.
The single included study suggesting that acupuncture may be safe and efficacious in CFS is limited in applicability by the use of sham acupuncture as the control. Integration and interface between naturopaths and conventional rural care: empirical findings from a grass-roots research project. The worsening epidemic of DM in the United States, along with the increasing prevalence of obesity, insulin resistance, and IGT, render the identification of promising interventions for these states a matter of some urgency. Jon Adams, University of Queensland, School of Population Health ,University of Qld, Herston, Queensland, 4006, Australia. While lifestyle interventions based on dietary pattern and physical activity can delay or prevent the onset of diabetes and reduce cardiovascular risk, adherence at the population level is severely limiting. Pharmacotherapy offers promise for diabetes prevention, but with associated high costs, unacceptability to many patients, and potential toxicity. In this context, the potential role of chromium (Cr), an insulin cofactor, in IGT is of great interest. Proposed, therefore, is a randomized, double-blind, placebo-controlled pilot trial conducted at the Yale Prevention Research Center to investigate the effects of daily Cr for 6 months at 2 dose levels on serum measures of glucose tolerance and on endothelial function in adults with IGT, IFG, and IR.
The study is powered to detect a clinically meaningful effect of Cr supplementation at either dose on glucose control, and to compare the two doses for equivalence. The study will investigate effects of Cr on both measures of glucose tolerance (glucose, insulin, OGTT) and brachial artery endothelial function, thus combining serum measures with a physiologic test of Cr effects on the vasculature.
The proposed study will generate much needed data regarding the efficacy of Cr in those at risk for type 2 diabetes and offers the promise of guiding practice, as well as directing future study. By contributing to knowledge related to potential diabetes prevention strategies, this study addresses one of the more pressing public health issues in the United States today.
Risk to human subjects in this study is a minor increment over minimal due to the administration of nitroglycerin as a control in BARS testing. Secondary outcomes: (4) It will show improved well-being, as measured by elevated melatonin and DHEA. Unlike many relaxation therapies, energy healing requires no participation by the patient, a feature that makes it particularly attractive in the hospital setting, where patients are often anxious, depressed, in pain, or sedated. Despite the increasing use of energy healing, few studies have looked at its benefits and even fewer at its underlying mechanisms of action. In this pilot study, we examined the effects of an energy healing modality known as Reiki on the autonomic nervous system (ANS) and the hypothalamus-pituitary-adrenal (HPA) axis, both of which participate in the stress response and stress-induced pain and disease progression. Subjects rested for 10 min before baseline heart rate and blood pressure were measured and blood was drawn to determine cortisol, ACTH, and DHEA levels, using commercial immunoassay kits. Subjects then received a 30- to 45-min Reiki or Pretend Reiki session followed immediately by post-session heart rate and blood pressure measurements and at 2h by blood draws. When asked whether they thought they were in the Reiki or Pretend Reiki group, about 70% of the participants reported that they believed that they had received a true Reiki session.
This suggests that the beneficial effects of Reiki on physiology, as compared to the Pretend Reiki, cannot be explained solely by the placebo effect.
Issac Amponsah, Faculty of Pharmacy Kwame Nkrumah University of SC, Knust, Kumasi, 233, Ghana.
Effects of ultra-low dilutions of sabal serrulata on human prostate cancer growth: mechanistic studies. Hakima Amri, Georgetown University, Basic Science Bldg, 3900 Reservoir Rd NW, Washington, DC 20007. Finally, serum protein differential expression was carried out using 2-dimensional gel electrophoresis followed by mass spectrometry analysis.
Effect of mind-body medicine skills on elements of emotional intelligence in medical students. Yet studies have reported that traits such as altruism and empathy tend to decline throughout medical school training. In an effort to foster medical student self-awareness and mindfulness, which may improve their EI, Georgetown University School of Medicine (GUSOM) offers an experiential course to undergraduate medical students in mind-body medicine skills.
The purpose is to expose students to a variety of mind-body approaches including meditation, imagery, as well as group sharing and listening generously for self-awareness and reflection. The aim of this study was to assess the impact of the Mind Body Medicine Skills (MBS) course on perceived stress, mindfulness, and elements of EI including intrapersonal capacities (attention to feelings, mood repair, clarity of feelings) and interpersonal capacities (perspective-taking, empathetic concern, and personal distress in response to distress in others). The intervention group (n=30) was comprised of first year medical students who self-selected to participate in this elective. The control group (n=36) included students from the first year class who completed the surveys but did not take the MBS course. Four questionnaires were completed at the start and end of the spring semester by all study participants: the Perceived Stress Scale (PSS), the Mindful Attention Awareness Scale (MAAS), and a survey of EI developed by Stratton et al (2005) comprised of the Trait Meta-Mood Scale and the Interpersonal Reactivity Index. ANCOVA was used to compare the MBS and the control groups at the end of the semester, controlling for beginning scores.
Patient perspectives of integrative and primary care management of back and neck paina€”qualitative findings from a randomized clinical trial.
These conditions are additionally some of the most common reasons why patients use complementary therapies, often without dialogue with conventional care providers. The focus groups were conducted separately for those in the integrative vs the conventional treatment groups. The interview data were transcribed ad verbatim and analyzed utilizing inductive content analysis technique. Eliane Angst, UCLA Center for Excellence in Pancreatic Diseases, 675 Charles E Young Drive South, Los Angeles, CA 90095.
A significant reduction in cell numbers was seen with quercetin concentrations of ~30 AµM and a maximum effect at ~75 AµM.
In MIA PaCa-2 cells a ~65% reduction in cell number was seen with 75 AµM of quercetin after 48 hours. Starved BxPC-3 cells treated with 75 AµM quercetin showed a ~95% reduction in cell number after 48 hours. Conclusion: These results suggest that quercetin has a potent growth-inhibitory effect in pancreatic cancer cells in vitro. Additional experiments to investigate the underlying mechanism of growth inhibition and animal studies are underway.
Flovanoids may reveal to be potent anticancer drugs found in our daily food, leading to specific diet recommendations. These can be taken together to qualify as an academic minor in many of the conventional MA or PhD programs, often forming the basis of a thesis or dissertation required for the terminal degree. In the fall of 2009, the university will launch a doctorate of nursing practice with a focus in integrative health and healing. Georgetown University developed a concentration of CAM within its Masters in Physiology program in 2003. We address the multicultural perspective, comparing data collected in Canada and Europe to those in the United States. The reason for this is that results on the health-promoting effects of spirituality and religiosity cannot easily be transferred from the United States to countries with different cultural and religious backgrounds. Thus, one has to recognize different concepts of spirituality, different attitudes towards its utilization, and objections against the implementation of it in a particular medical system.
In Germany, 3 colleagues have founded the Transdisciplinary Working Group on Spirituality and Health, and in Canada the Canadian Research Network on Spirituality and Health has been active for a couple of years. Data and approaches from these different networks will be combined into this symposium.Dr BA?ssing is an associate professor at the University of Witten, Herdeckea€™s Faculty of Medicine, where he directs the research group Spirituality and Health. The effect of a€?acupuncture for losing weighta€? on the level of blood sugar: a survey on the mechanism. Hoda Azizi, Beijing University of Chinese Medicine, 11 Bei San Huan Dong Lu, Beijing, Beijing, 100029, China. Material and Methods: In this clinical trial study, 66 patients were included in case and control groups. Blood sugar was examined just before inserting needles and immediately after withdrawal of needles. Conclusion: Our results suggest that the mechanism of acupuncture in losing weight is significantly related to making an increase in BS.
John Balletto, Center for Muscular Therapy, Inc, 545 Pawtucket Avenue, Mailbox 304, Pawtucket, RI 02860-6046. As with business startups that begin informally and successfully mature into larger enterprises, growth brings new organizational challenges, together with greater visibility and opportunity. The maturation of massage as a healthcare profession increases the need for a process to formalize the synthesis of massage therapy knowledge from clinical experience and research—to collect what we know and to make such baseline knowledge widely available to practitioners, consumers, and other healthcare stakeholders. The present paper lays out the motivations and framework for creating massage therapy guidelines that are informed both by research and by clinical experience.
It also acts as a report to the massage therapy profession and to other stakeholders about the work of the Best Practices Committee of the Massage Therapy Foundation since 2006. And it has the additional goal of providing a healthcare literature basis for future academic discussions of massage.
The discussion here is based on a definition from the Institute of Medicine and on research into the nature of expertise.
Topics addressed include guideline creation, credentialing of complementary and alternative medicine practitioners, definition of competence, and the increasing role of technology (that is, informatics) in managing training and task-necessary competencies. The roles of transparency and a wide and open peer review are emphasized as essential to the usability and credibility of guidelines. Health Canada issues consumer advisories regarding the safety of marketed health products, yet the criteria for issuing advisories have not been evaluated for consistency or objectivity.
The Causality Algorithm used by Health Canada was used to rate degree of association between the adverse events (AEs) and the products.
The Severity of Adverse Events Scale, developed by the National Cancer Institute, was used to determine the severity of the AEs. Most NHP AWRs were issued based on potential AEs from contamination and adulteration, whereas most of the AWRs for therapeutic drugs were issued due to actual AEs. Of the 6 NHP AWRs issued for actual AEs, 3 (50%) were unassessable for severity, whereas of the 28 AWRs issued for actual therapeutic drug AEs, 1 (3%) was unassessable for severity. The origin of reports for NHPs tended to be from foreign sources or Health Canada, whereas reports for therapeutic drugs were mostly issued by Health Canada in conjunction with drug manufacturers. The potential of a mistletoe (Viscum album L) extract to alleviate adverse effects of cancer chemotherapy: an in vitro study. Stephan Baumgartner, University of Bern, Institute of Complementary Medicine KIKOM, Inselspital, Bern, BE, 3010, Switzerland. We investigated the effect of a mistletoe extract on PBMC with and without concomitant treatment with cyclophosphamide and compared viability and replication of normal PBMC with that of a T-cell leukemia cell line. The results motivate further preclinical and clinical investigations of mistletoe extracts as an adjuvant medication in cancer therapy to alleviate side effects of conventional therapy. Stephan Baumgartner, Institute of Complementary Medicine KIKOM, University of Bern, Inselspital, Imhoof-Pavillon, Bern, BE, 3010, Switzerland. We investigated the potential of a commonly used plant pathogen–system, Arabidopsis thaliana infected with the virulent bacteria Pseudomonas syringae (pv tomato strain DC3000), regarding its response towards a homeopathic treatment.
Compared to Bion (a common SAR inducer used as positive control), the magnitude of the treatment effect of Biplantol was about 50%.
None of the other tested preparations yielded significant effects in the overall evaluation. The purpose of this study was to determine remedy effects on a common quantitative measure of complexity, the correlation dimension (D2), of human sleep electroencephalography (EEG).
High Hostile subjects increased complexity at C3 and Pz, but decreased complexity at O2 during stage 3 sleep on CC. In the high Anxiety-Sensitive subjects, CC caused significant increases in complexity at Pz and O1 during stage 3 sleep and at C3, C4, and Pz during stage 4 sleep.
CC increased complexity significantly at Cz, C4, and O2 during REM sleep in only the high Anxiety-Sensitive subjects. The purpose of the present study was to determine whether or not the objective measure of polysomnographically-recorded all-night sleep recordings can distinguish verum homeopathic remedies from placebo in human subjects. NV produced more marked effects on increased shifts in sleep stages, with a growth in effects from night 22 to 23. This study examined the effects of olfactory administration of a polycrest homeopathic remedy Sulphur on heart rate variability (HRV).
The Sulphur was given at dilution factors used for preparing 6c, 12c, and 30c potencies (1 potency per session, with potency order randomized), but for each potency, the test solutions were succussed to different degrees (stirred without shaking, 10, 20, or 100 succussions). Homeopathic remedies increase spectral electroencephalographic power during sleep in healthy young adults. The purpose of the present study was to assess the effects of verum vs placebo homeopathic remedies on spectral qEEG measures of polysomnographically-recorded all-night sleep recordings. Evaluating a nonlinear dynamical model for human flourishing: Relationship of PANAS positive-to-negative-affect ratio and global health and well-being. The purpose of the present study was to compare global physical health (GPH) and well-being ratings of young adults whose P:N mood ratios fell above vs below the Losada line. Despite higher (MCSD) scores in PF, a small sex and age difference between groups, ANCOVAs controlling for MCSD, sex, and age still showed statistical significance of the above PF vs PL group differences. Gurjeet Birdee, Osher Research Center Harvard Medical School, 401 Park Drive, Suite 22-A West, Boston, MA 02215. We identified the prevalence of CAM modalities used and the characteristics of users among the pediatric population.



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